What is the difference between CBD and THC?

What is the difference between CBD and THC?

Products are grown (flower) and extracted (concentrates & MIPs) using a state of the art cultivation facility and laboratory-grade extraction and purification techniques to create safe, precise medical marijuana products. Each type of medical marijuana product has different levels of naturally occurring compounds found in the cannabis plant.

Tetrahydrocannabinol (THC) and cannabidiol (CBD) are two primary types of cannabinoids found naturally in the cannabis plant. These two substances interact differently with the cannabinoid receptors found in the human body, bringing about two very different effects to the patient:

CBD Only Products

CBD has the same chemical formula as THC, but the atoms are arranged differently. This slight variance causes THC to create a psychoactive effect while CBD lacks such an influence.

CBD accounts for a large amount of the cannabis extract. Its plentiful nature, coupled with its very limited psychoactive effect, makes it a strong candidate for medical applications.

The effects of CBD include:

  • Reduction of psychoactive symptoms
  • Relief from convulsions and nausea
  • Decreased anxiety
  • Decreased inflammation

THC Products

THC is the main psychoactive component of the marijuana plant. This compound works by imitating the effects of anandamide, a neurotransmitter produced naturally by the human body to help modulate sleeping and eating habits, as well as the perception of pain.

The effects of THC include:

  • Relaxation
  • Altered senses of sight, smell, and hearing
  • Fatigue
  • Hunger
  • Reduced aggression


  • Bergamaschi M.M., Queiroz R.H., Zuardi A.W., Crippa J.A. Safety and side effects of cannabidiol, a Cannabis sativa constituent.Curr Drug Saf. 2011 Sep 1; 6(4):237-49.
  • Carter GT1, Weydt P, Kyashna-Tocha M, Abrams DI. Medicinal cannabis: rational guidelines for dosing. IDrugs. 2004 May; 7(5):464-70.
  • Grotenhermen Franjo. 2003. Clinical Pharmacokinetics of Pharmacodynamics of Cannabinoids. Clinical Pharmacokinetics. 42(4): 327-60.
  • Russo E., Guy G.W. A tale of two cannabinoids: the therapeutic rationale for combining tetrahydrocannabinol and cannabidiol. Medical Hypotheses. 2006; 66(2):234-246.

THC & CBD Products Now Available

Curaleaf offers a range of safe, legal, low-THC and full-strength cannabis products made using the industry’s cleanest, most medically precise extraction and purification methods.

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